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Anti-NALP3 / NLRP3 Antibody (aa81-93) LS-C112945


Wt. Vol. Conc. Price
100 µg - - $275
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NALP3 / NLRP3 Antibodies

Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766
Goat Polyclonal to Human NALP3 / NLRP3
IHC - Paraffin, ELISA
Immunohistochemistry Image
Anti-NALP3 / NLRP3 Antibody (aa1-50) LS-C148764
Rabbit Polyclonal to Human NALP3 / NLRP3
Human, Monkey, Mouse, Rat
Western blot

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human NALP3 / NLRP3
Human, Monkey


Human NALP3 / NLRP3
Human, Monkey (tested or 100% immunogen sequence identity)
Bat, Pig (at least 90% immunogen sequence identity)
Immunoaffinity purified


ELISA (1:32000)

Specificity and Use

NALP3 / NLRP3 antibody was raised against synthetic peptide RDLYEKAKRDEPK-C from the N-terminus (near) of human NLRP3 (NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Panda, Bat, Pig (92%); Dog, Bovine, Rabbit (85%).
LS-E27308 - Lyophilized - 100 µg - $145.00
Human NLRP3. This antibody is expected to recognize all reported isoforms (NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 36kDa band in Human Peripheral Blood Mononucleocytes lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the smallest calculated size of 106kDa according to NP_899632.1. The 36kDa band was successfully blocked by incubation with the immunizing peptide.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About NALP3 / NLRP3

Q96P20 NM_004895 NP_004886.3

NLRP3 Antibody, AGTAVPRL Antibody, AII Antibody, C1orf7 Antibody, Caterpiller protein 1.1 Antibody, Cryopyrin Antibody, FCAS Antibody, FCU Antibody, PYPAF1 Antibody, NALP3 Antibody, CIAS1 Antibody, CLR1.1 Antibody, MWS Antibody

NALP3 / NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.

Requested From: United States
Date Requested: 10/25/2016

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