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Anti-NALP3 / NLRP3 Antibody (aa4-223, clone 1D4B) LS-C189819

Ordering

Wt. Vol. Conc. Price
100 µg 100 µl 0.5 mg/ml $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NALP3 / NLRP3 Antibodies

Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766
Goat Polyclonal to Human NALP3 / NLRP3
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NALP3 / NLRP3 Antibody (N-Terminus) IHC-plus™ LS-B4321
Rabbit Polyclonal to Human NALP3 / NLRP3
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-NALP3 / NLRP3 Antibody (aa1-50) LS-C148764
Rabbit Polyclonal to Human NALP3 / NLRP3
Human, Monkey, Mouse, Rat
Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 1D4B] (IgG1) to Human NALP3 / NLRP3
Human
ICC
Unconjugated

Details

Human NALP3 / NLRP3
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1D4B]
Unconjugated
Affinity purified
Unmodified

Applications

ICC (8 - 25 µg/ml)

Specificity and Use

NALP3 / NLRP3 antibody was raised against recombinant corresponding to aa4-223 from human NALP3 expressed in E.coli.
aa4-223
Human NALP3. Does not react with recombinant human NALP1, 2, 5, rhNALP3 aa540-689, or recombinant mouse NALP3.

Packaging

Lyophilized from PBS, trehalose
100 µl Sterile PBS to 0.5mg/ml.
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C.
For research use only.

About NALP3 / NLRP3

Q96P20 NM_004895 NP_004886.3

NLRP3 Antibody, AGTAVPRL Antibody, AII Antibody, C1orf7 Antibody, Caterpiller protein 1.1 Antibody, Cryopyrin Antibody, FCAS Antibody, FCU Antibody, PYPAF1 Antibody, NALP3 Antibody, CIAS1 Antibody, CLR1.1 Antibody, MWS Antibody

NALP3 / NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.

Requested From: United States
Date Requested: 12/6/2016

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