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Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766

Note: This antibody replaces LS-C47546, LS-C73142, LS-C122195


Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular NALP3 / NLRP3 Antibodies

Anti-NALP3 / NLRP3 Antibody (aa1024-1036) IHC-plus™ LS-B1766
Goat Polyclonal to Human NALP3 / NLRP3
IHC - Paraffin, ELISA
Immunohistochemistry Image
Anti-NALP3 / NLRP3 Antibody (aa1-50) LS-C148764
Rabbit Polyclonal to Human NALP3 / NLRP3
Human, Monkey, Mouse, Rat
Western blot

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human NALP3 / NLRP3
IHC - Paraffin, ELISA


Human NALP3 / NLRP3
Human (tested or 100% immunogen sequence identity)
Monkey, Rat, Horse, Rabbit (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • IHC - Paraffin (2.5 µg/ml)
  • ELISA (1:32000)

Specificity and Use

NALP3 / NLRP3 antibody was raised against synthetic peptide C-EKPELTVVFEPSW from the C-terminus of human NLRP3 (NP_001073289.1; NP_004886.3; NP_899632.1; NP_001120933.1; NP_001120934.1). Percent identity by BLAST analysis: Human, Gibbon (100%); Monkey, Marmoset, Rat, Rabbit, Horse (92%); Mouse, Bovine, Panda (85%).
LS-E25465 - Lyophilized - 100 µg - $145.00
Human NLRP3. Variants (NP_001073289.1; NP_004886.3) encode the same isoform.
Immunohistochemistry: LS-B1766 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1766 was determined to be 2.5 ug/ml.


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About NALP3 / NLRP3

Q96P20 NM_004895 NP_004886.3

NLRP3 Antibody, AGTAVPRL Antibody, AII Antibody, C1orf7 Antibody, Caterpiller protein 1.1 Antibody, Cryopyrin Antibody, FCAS Antibody, FCU Antibody, PYPAF1 Antibody, NALP3 Antibody, CIAS1 Antibody, CLR1.1 Antibody, MWS Antibody

NALP3 / NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.


Anti-NLRP3 antibody IHC of human peripheral blood leukocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1766 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/21/2016

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