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Anti-NALP1 / NLRP1 Antibody (C-Terminus) IHC-plus™ LS-B589

Note: This antibody replaces LS-C19469

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular NALP1 / NLRP1 Antibodies

Anti-NALP1 / NLRP1 Antibody (aa323-372) IHC-plus™ LS-B5845
Rabbit Polyclonal (IgG) to Human NALP1 / NLRP1
Human, Monkey, Mouse, Bovine, Dog, Horse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-NALP1 / NLRP1 Antibody (C-Terminus) IHC-plus™ LS-B589
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human NALP1 / NLRP1
Human
IHC - Paraffin, ICC, Western blot
Unconjugated

Details

Human NALP1 / NLRP1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Purified IgG
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • ICC
  • Western blot (1 - 2 µg/ml)

Specificity and Use

NALP1 / NLRP1 antibody was raised against synthetic peptide from human NLRP1 / NALP1.
LS-E29998 - Liquid - 50 µg - $145.00
C-Terminus
peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
Immunohistochemistry: LS-B589 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B589 was determined to be 2.5 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About NALP1 / NLRP1

Q9C000 NM_014922 NP_055737.1

NLRP1 Antibody, CLR17.1 Antibody, CARD7 Antibody, DEFCAP Antibody, DEFCAP-L/S Antibody, NAC Antibody, SLEV1 Antibody, VAMAS1 Antibody, KIAA0926 Antibody, NALP1 Antibody, PP1044 Antibody

NALP1 / NLRP1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells.

Immunohistochemistry

Immunohistochemistry
Anti-NLRP1 / NALP1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B589 concentration 5 ug/ml.

Immunocytochemistry

Immunocytochemistry
Immunocytochemistry of NALP1 in K562 cells with NALP1 antibody at 10 ug/ml.

Immunofluorescence

Immunofluorescence
Immunofluorescence of NALP1 in K562 cells with NALP1 antibody at 20 ug/ml.

Western blot

Western blot
Western blot of NALP1 in U937 cell lysate with NALP1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.

Requested From: United States
Date Requested: 12/9/2016

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