Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
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order histories, retained contact details for faster checkout, review submissions, and special promotions.
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Ammonium sulfate precipitation
Unmodified
Applications
IHC
IHC - Paraffin (1:10 - 1:50)
Western blot (1:1000)
Specificity and Use
LS-E787 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C98654. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa99-130
This HBO1/MYST2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human HBO1/MYST2.
Packaging
PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.
Formalin-fixed and paraffin-embedded human testis tissue reacted with HBO1/MYST2 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot
HBO1/MYST2 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The HBO1/MYST2 antibody detected the HBO1/MYST2 protein (arrow).