Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Mouse (at least 90% immunogen sequence identity)
Western blot (1:5000)
Specificity and Use
MYOD / MYOD1 antibody was raised against a genomic peptide made to an N-terminal region of the human MyoD1 protein (within residues 1-150). [Swiss-Prot P15172]. Percent identity by BLAST analysis: Mouse (90%).
PBS, 0.1% BSA, 50% glycerol, 0.05% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins.