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MYL12A / MRCL3

Myosin, Light Chain 12A, Regulatory, Non-sarcomeric

MYL12A / MRCL3 is a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.

Gene Name: Myosin, Light Chain 12A, Regulatory, Non-sarcomeric
Synonyms: MYL12A, MRCL3, MLCB, MRLC3, MYL2B, MLC-2B
Target Sequences: NM_006471 NP_006462.1 P19105

☰ Filters
Antibodies (14)
Proteins (5)
Over-Expression Lysate (2)
Primary (14)
Recombinant (3)
MYL12A / MRCL3 (19)
Human (14)
Mouse (3)
Rat (3)
IHC (7)
IHC-P (2)
WB (12)
ELISA (4)
IF (1)
IP (1)
Peptide-ELISA (1)
rabbit (14)
Product Group
IHCPlus (2)
IgG (6)
polyclonal pc (14)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (7)
aa10-171 (8)
pSer18 (1)
pSer19/20 (1)
pThr17/Ser18 (1)
No (19)
His (2)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Purified (1)
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (pThr17/Ser18) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
MYL12A / MRCL3 Antibody - Immunohistochemistry with anti-myosin pS19/pS20 antibody showing strong cytoplasmic staining of myocytes in mouse heart muscle 20x and 40x (B & C). Staining was performed on Leica Bond system using the standard protocol. Formalin fixed/paraffin embedded tissue sections were subjected to antigen retrieval and then incubated with rabbit anti-myosin pS19/pS20 antibody at 1:100 dilution for 60 minutes. Biotinylated Anti-rabbit secondary antibody was used to detect primary antibody. The reaction was developed using streptavidin-HRP conjugated compact polymer system and visualized with chromogen substrate, 3’3-diamino-benzidine substrate (DAB). The sections were then counterstained with hematoxylin to detect cell nuclei.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (pSer19/20) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
25 µl/$304
MYL12A / MRCL3 Antibody - Western blot analysis of extracts from LOVO cells, treated with H2O2 (100uM, 30mins), using Myosin regulatory light chain 2 (Phospho-Ser18) antibody.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (pSer18) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
MYL12A / MRCL3 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
MYL12A / MRCL3 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
MYL12A / MRCL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$351; 200 µl/$410; 500 µl/$615; 1 ml/$769
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$329; 200 µl/$379; 500 µl/$549; 1 ml/$651
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$361; 200 µl/$426; 500 µl/$663; 1 ml/$822
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$426; 200 µl/$518; 500 µl/$913; 1 ml/$1,080
MYL12A / MRCL3 Antibody - Western blot of recombinant MYL12A / MRCL3.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
MYL12A / MRCL3 Rabbit anti-Human Polyclonal (aa10-171) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$533; 200 µl/$709; 500 µl/$1,229; 1 ml/$1,537
MYL12A / MRCL3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
19.6 kDa
100 µg/$494
MYL12A / MRCL3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
19.6 kDa
20 µg/$150
MYL12A / MRCL3 Protein - Purified recombinant protein MYL12A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
19.6 kDa
20 µg/$1,107
MYL12A / MRCL3 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
MYL12A / MRCL3 Protein - Recombinant Myosin Light Chain 12A By SDS-PAGE
Select
E. coli
His
20.3 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
Viewing 1-19 of 19 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).