Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse (tested or 100% immunogen sequence identity)
IHC - Frozen (1:200)
Specificity and Use
Murine macrophage precursor cells
Multiple antigens were precipitated by ER-MP54 under reducing and non-reducing conditions: Major bands could be detected at 90, 85-80 and 75-70 kDa, at lower amounts at 45kDa and less frequently at 27 and 12 kDa. Antigen distribution: Isolated cells: The antigen is present on bone marrow myeloid cells up to monoblasts where the antigen is localized in the cytoplasm. Under specific experimental in vitro conditions, treatment by glucocorticoids, the antigen can also be detected on the cell surface. Tissue sections: The antigen can be detected in bone marrow plugs and some clusters of red pulp in spleen. Specificity: Mouse: Myeloid precursors up to monoblats, cytoplasmatic antigen Other species: unknown
Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal