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Anti-Myc Tag Antibody (aa423-435, clone 9E10, FITC) LS-C46410


Wt. Vol. Conc. Price
100 µg - - $320
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 9E10] (IgG1) to Human Myc Tag
Flow Cytometry
FITC Conjugated


Human Myc Tag
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [9E10]
Protein G purified


Flow Cytometry (1:200)

Specificity and Use

Myc Tag antibody was raised against synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-myc. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Orangutan, Monkey, Marmoset, Tamarin (92%); Rat, Sheep, Hamster, Panda, Dog, Horse (85%).
The antibody 9E10 may be used to detect the c-Myc tag. The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:200. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. Application note: Membrane


PBS, 15 mM sodium azide, approx., pH 7.4.
Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
For research use only.

About Myc Tag

Requested From: United States
Date Requested: 10/22/2016

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