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Anti-Myc Tag Antibody (aa423-435, clone 9E10, FITC) LS-C46410

Ordering

Wt. Vol. Conc. Price
100 µg - - $320
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 9E10] (IgG1) to Human Myc Tag
Human
Flow Cytometry
FITC Conjugated

Details

Human Myc Tag
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [9E10]
Fluorescein
Protein G purified
Unmodified

Applications

Flow Cytometry (1:200)

Specificity and Use

Myc Tag antibody was raised against synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-myc. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%); Orangutan, Monkey, Marmoset, Tamarin (92%); Rat, Sheep, Hamster, Panda, Dog, Horse (85%).
aa423-435
The antibody 9E10 may be used to detect the c-Myc tag. The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells
The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1:200. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator. Application note: Membrane The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 15 mM sodium azide, approx., pH 7.4.
Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
For research use only.

About Myc Tag


Requested From: United States
Date Requested: 12/6/2016

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