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MYC / c-Myc
v-myc avian myelocytomatosis viral oncogene homolog
MYC / c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
| Gene Name: | v-myc avian myelocytomatosis viral oncogene homolog |
| Synonyms: | MYC, BHLHe39, C-Myc, MRTL, Myc proto-oncogene protein, Proto-oncogene c-Myc, Rats1, Transcription factor p64, v-myc |
| Target Sequences: | NM_002467 NP_002458.2 P01106 |
Publications (25)
1
Characterization of monoclonal antibodies reactive to several biochemically distinct human cytomegalovirus glycoprotein complexes. Kari B, Lussenhop N, Goertz R, Wabuke-Bunoti M, Radeke R, Gehrz R. Journal of virology. 1986 60:345-52.
[PubMed:3021969]
[PMC:PMC288899]
2
The ornithine decarboxylase gene is a transcriptional target of c-Myc. Bello-Fernandez C, Packham G, Cleveland JL. Proceedings of the National Academy of Sciences of the United States of America. 1993 90:7804-8.
[PubMed:8356088]
[PMC:PMC47231]
3
Association of the class V myosin Myo4p with a localised messenger RNA in budding yeast depends on She proteins. Mnchow S, Sauter C, Jansen RP. Journal of cell science. 1999 1511-8. (IP; Yeast)
[PubMed:10212145]
☰ Filters
Products
Antibodies
(292)
ELISA Kits
(30)
Proteins
(12)
Type
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(1)
Cell-Based Phosphorylation
(2)
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(1)
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(6)
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(1)
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(2)
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(2)
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(287)
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(10)
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(16)
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(1)
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(5)
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MYC / c-Myc
(334)
Reactivity
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(264)
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(111)
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(82)
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(4)
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(1)
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(4)
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(9)
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(15)
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(19)
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(4)
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(4)
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(4)
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(1)
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(2)
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(106)
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(2)
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(32)
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(43)
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(8)
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(2)
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(4)
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(3)
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(2)
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(2)
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(1)
Clonality
monoclonal mc
(94)
polyclonal pc
(181)
recombinant monoclonal rmc
(17)
Clone
1788CT320.61.28
(1)
1G7
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33A12E10
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(1)
9E10
(30)
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(3)
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(2)
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(2)
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(2)
Format
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(4)
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(5)
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(21)
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(1)
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(3)
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(2)
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(12)
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(2)
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(2)
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(2)
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(10)
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(1)
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(24)
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(8)
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(4)
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(2)
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(2)
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(2)
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(2)
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(2)
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(23)
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(22)
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(1)
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(12)
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(2)
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(5)
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(3)
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(172)
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(19)
c-myc epitope tag
(16)
pThr58
(14)
pSer62
(13)
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(10)
aa184-454
(8)
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(8)
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(8)
Ser373
(7)
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(7)
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(7)
aa408-438
(6)
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(5)
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(4)
aa410-419
(4)
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(4)
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(3)
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(3)
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(1)
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(1)
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(1)
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(1)
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(1)
Arg367
(1)
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(1)
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(1)
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(1)
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(1)
aa31-80
(1)
aa325-374
(1)
aa400-450
(1)
aa408-420
(1)
aa421-439
(1)
p358
(1)
p373
(1)
p58
(1)
p62
(1)
Publications
No
(333)
Yes
(1)
Sample Type
Adherent Cell Cultures
(3)
Cell Culture Supernatants
(1)
Cell Lysates
(7)
Nuclear Lysates
(3)
Plasma
(11)
Serum
(11)
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(7)
Tag
6His, N-terminus
(2)
GST
(1)
GST, N-terminus
(2)
His, N-Terminal
(1)
His-GST
(2)
His-GST, N-terminus
(1)
Myc-DDK (Flag)
(3)
Species
Human
(9)
Mouse
(2)
Source
293T Cells
(1)
E. coli
(7)
HEK 293 Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(3)
Cancer Pathology
Cancer
MYC / c-Myc Mouse anti-Human Monoclonal (aa408-439) (9E10) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
Cancer Pathology
Cancer
MYC / c-Myc Mouse anti-Human Monoclonal (aa400-450) (9E10) Antibody
All species, Human
Flo, IHC, IHC-P, IP, WB
Unconjugated
0.05 mg/$460
MYC / c-Myc Mouse anti-Human Monoclonal (aa423-435) (FITC) (9E10) Antibody
All species, Human
Flo, IHC-P, IP, WB
FITC Conjugated
0.1 mg/$368
Cancer Pathology
Cancer
MYC / c-Myc Rabbit anti-Human Polyclonal (aa25-74) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$460
MYC / c-Myc Rabbit anti-Human Polyclonal (aa 398-439) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
MYC / c-Myc Mouse anti-Human Monoclonal (OTI5G3) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
MYC / c-Myc Mouse anti-Human Monoclonal (9E10) Antibody
Mouse, Human
ELISA, Flo, IF, IHC, IP, WB
Unconjugated
0.1 ml/$386
![MYC / c-Myc Antibody - Western Blot: c-Myc Antibody (9E10) [Biotin] - Analysis of c-myc in Jurkat cell lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.](https://lsbio-7d62.kxcdn.com/image2/myc-c-myc-antibody-clone-9e10-biotin-ls-c180004/135929_1455644.jpg)
MYC / c-Myc Mouse anti-Human Monoclonal (Biotin) (9E10) Antibody
Drosophila, Mouse, Human
ELISA, Flo, ICC, IF, IHC, IHC-Fr, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
MYC / c-Myc Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Dog, Sheep, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
MYC / c-Myc Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Dog, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
MYC / c-Myc Sheep anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
E. coli
6His, N-terminus
52.8 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
E. coli
6His, N-terminus
51 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
E. coli
His-GST, N-terminus
65kDa
10 µg/$339; 50 µg/$802; 200 µg/$1,430; 1 mg/$2,728; 5 mg/$5,601; 2 mg/$2,988
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
DNA Binding Phosphorylation
12 x 8-Well Microstrips
Mouse, Human
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$735
MYC / c-Myc Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
MYC / c-Myc Mouse anti-Human Monoclonal (C-Terminus) (Azide-free, BSA-free) (MVH39-1) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
E. coli
GST, N-terminus
53 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
MYC / c-Myc Rabbit anti-Human Polyclonal (pThr58) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$328; 100 µl/$419
MYC / c-Myc Mouse anti-Human Monoclonal (OTI5E9G2) Antibody
Dog, Rat, Human, Monkey
IF, WB
Unconjugated
100 µl/$434
MYC / c-Myc Rabbit anti-Human Polyclonal (pThr58) Antibody
Chicken, Zebrafish, Pig, Mouse, Dog, Sheep, Bovine, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$315
MYC / c-Myc Rabbit anti-Human Polyclonal (pThr358) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
Viewing 1-25
of 334
product results
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