Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 9 E10] (IgG1) to Human MYC / c-Myc
Western blot, Immunoprecipitation
Human MYC / c-Myc
Human, Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [9 E10]
Western blot (1:100 - 1:500)
Specificity and Use
MYC / c-Myc antibody was raised against synthetic peptide corresponding to residues 408-439 of the human p62c-myc protein.
Recognizes an epitope located in the amino acid residue 410-419 of human oncogene product c-myc. This antibody reacts with both components of the p62c-myc-p64c-myc. This antibody cross reacts with human p62/64c-myc but does not react with mouse p62/64c-myc protein.
MYC / c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma.