Target
Human MYADM / Myeloid Marker BM-1
Synonyms
MYADM | Myeloid upregulated protein | SB135 | Protein SB135
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Ready-to-Use.
Also available
Unmodified or
Azide-free, BSA-free.
Immunogen
Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.
Specificity
Human MYADM / Myeloid Marker BM-1
Applications
- IHC
- IHC - Paraffin (1:1)
- Immunofluorescence
- Flow Cytometry
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Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody recognizes a 183kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.
Presentation
1X PBS, 0.1 mg/ml BSA, 0.05% sodium azide
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About MYADM / Myeloid Marker BM-1