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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MXI1 / MAD2 Antibody (clone 1F3) LS‑C197723
MAD2 antibody LS-C197723 is an unconjugated mouse monoclonal antibody to human MAD2 (MXI1). Validated for ELISA and WB.
Catalog
Size
Price
LS-C197723-100
100 µg
Unavailable

Popular MXI1 / MAD2 Products

Anti-MXI1 / MAD2 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8041 dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Zebrafish
Applications: IHC, IHC - Paraffin, Western blot
Immunofluorescence analysis of HeLa cells.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot
Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

MAD2 antibody LS-C197723 is an unconjugated mouse monoclonal antibody to human MAD2 (MXI1). Validated for ELISA and WB.
About MXI1 / MAD2
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. P50539 NM_005962 NP_005953.4

MXI1 Antibody, BHLHc11 Antibody, MAX dimerization protein 2 Antibody, MAX interactor 1 Antibody, MAD2 Antibody, MXI Antibody, MAX interacting protein 1 Antibody, MXD2 Antibody, Max-interacting protein 1 Antibody


Specifications

Target
Human MXI1 / MAD2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [1F3]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • Western blot
  • ELISA
Immunogen
MXI1 / MAD2 antibody was raised against mXI1 (NP_001008541.1, aa73-182 partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MXI1 / MAD2
Usage
Western Blot: Transfected lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.

Western blot

Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.

Western blot

Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.

Western blot

Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.
Western Blot analysis of MXI1 expression in transfected 293T cell line by MXI1 monoclonal antibody (M08), clone 1F3.Lane 1: MXI1 transfected lysate(26.1 KDa).Lane 2: Non-transfected lysate.


Requested From: 
Date Requested: 6/21/2018

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