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| Catalog Number | Size | Price |
|---|---|---|
| LS-B6201-50 | 50 µg | $440 |
![MVP / VAULT1 Antibody - Immunofluorescence of monoclonal antibody to MVP on HeLa cell. [antibody concentration 10 ug/ml]](https://lsbio-7d62.kxcdn.com/image2/pathplus-mvp-vault1-antibody-clone-2h3-1a6-ls-b6201/52308_75714.jpg)
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PathPlus™ Monoclonal Mouse anti‑Human MVP / VAULT1 Antibody (clone 2H3‑1A6, IHC, IF, WB) LS‑B6201
PathPlus™ Monoclonal Mouse anti‑Human MVP / VAULT1 Antibody (clone 2H3‑1A6, IHC, IF, WB) LS‑B6201
Note: This antibody replaces LS-C133616
Antibody:
MVP / VAULT1 Mouse anti-Human Monoclonal (2H3-1A6) Antibody
Application:
IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
MVP / VAULT1 Mouse anti-Human Monoclonal (2H3-1A6) Antibody
Application:
IHC-P, IF, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
MVP (VAULT1) is the major component of the vault complex, amulti-subunit ribonucleoprotein structure that participates in nuclear to cytoplasmic transport. MVP regulates MAP kinases, as well as the JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. It is found in smooth muscle and cardiac muscle, where it is involved in deciding cell fate and survival. It is further implicated in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804; Receptors Clin Investig. 2016;3(2). pii: e1310, PMID: 27275002
Target
Human MVP / VAULT1
Synonyms
MVP | Major vault protein | VAULT1 | LRP
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG2a,k
Monoclonal
Clone
2H3-1A6
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Immunogen
MVP (AAH15623, 1 aa ~ 894 aa) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MVP
Applications
- IHC - Paraffin (5 µg/ml)
- Immunofluorescence (10 µg/ml)
- Western blot (1:500 - 1:1000)
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. Sandwich ELISA: Recombinant protein. Western Blot using cell line lysates and the recombinant protein used as the immunogen.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MVP / VAULT1
Validation
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ MVP / VAULT1 Antibody (clone 2H3-1A6) for IHC, IF/Immunofluorescence, WB/Western, ELISA LS-B6201 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Species:
Mouse
Applications:
IHC, IHC - Frozen, Western blot
Species:
Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Reactivity:
Mouse
Range:
62.5-4000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/23/2024
Date Requested: 4/23/2024
