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Anti-MUC5AC Antibody (clone CLH2) LS-C152909

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $375
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MUC5AC Antibodies

Anti-MUC5AC Antibody (clone CLH2) IHC-plus™ LS-B2434
Mouse Monoclonal [clone CLH2] (IgG1) to Human MUC5AC
Human
IHC - Paraffin, IHC - Frozen, ICC, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MUC5AC Antibody (clone 1-13M1) IHC-plus™ LS-B5563
Mouse Monoclonal [clone 1-13M1] (IgG1) to Human MUC5AC
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MUC5AC Antibody (clone 2-12M1) LS-C146614
Mouse Monoclonal [clone 2-12M1] (IgG1) to Human MUC5AC
Human, Monkey, Mouse, Bovine, Cat
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone CLH2] (IgG1) to Human MUC5AC
Human
IHC - Paraffin, ICC, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human MUC5AC
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [CLH2]
Unconjugated
Purified
Unmodified

Applications

  • IHC - Paraffin (1:1000 - 1:2000)
  • ICC
  • Western blot
  • Immunoprecipitation
  • ELISA

Specificity and Use

MUC5AC antibody was raised against directed against a synthetic peptide of the MUC5AC tandem repeat
Antibody MAB2011 is specific for the MUC5AC tandem repeat of human mucin. No cross reactivity with other peptides from MUC2, 3, 6, or 7. Immunoreactivity of MAB2011 has been detected in the following normal human epithelial tissues: bronchus, endocervix, stomach, and gallbladder. The predominant staining pattern in normal tissues is perinuclear. Antibody reactivity has been observed in foveolar and mucopeptic neck cells of normal gastric mucosa. The expression of MUC5AC has been frequently observed in gastric carcinomas and may be used as a marker of gastric differentiation. The CLH2 antibody shows a weak reactivity with a high molecular weight smear characteristic of mucin from native mucin extract from normal gastric mucosa and from gastric diffuse carcinoma. The antibody was generated by immunizing mice with a synthetic tandem repeat peptide The antibody recognizes the sequence TTSTTSAP within the tandem repeat of MUC5AC (1). It further recognizes glycosylated as well as unglycosylated MUC5AC
Western blot: Clone CLH2 shows a weak reactivity with a high molecular weight smear characteristic of mucin from a native mucin extract from normal gastric mucosa and from gastric diffuse carcinoma. Typical dilution is 1:100. Immunocytochemistry. Immunohi

Packaging

0.02 M phosphate buffer, pH 7.6, 0.25 M sodium chloride, 0.1% sodium azide
+4°C. Store undiluted.
For research use only.

About MUC5AC

P98088 AJ001403 CAA04738.1

MUC5AC Antibody, Gastric mucin Antibody, Major airway glycoprotein Antibody, Muc5/5ac Antibody, Mucin-5AC Antibody, LeB Antibody, Lewis B blood group antigen Antibody, Tracheobronchial mucin Antibody, TBM Antibody, MUC-5AC Antibody, MUC5 Antibody

MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is involved in epithelial cell proliferation and differentiation in adult airway mucosa and can be used as a marker for hypersecretory disorders. MUC5AC has also been observed in various tumors.

Immunohistochemistry

Immunohistochemistry
IHC: Staining of foveolar epithelium of human gastric mucosa. Detection with a biotin-conjugated rabbit anti-mouse secondary, followed by avidin-biotin peroxidase complex.

Immunohistochemistry

Immunohistochemistry
IHC: Staining of foveolar epithelium of human gastric mucosa. detection with a biotin-conjugated rabbit anti-mouse secondary, followed by avidin-biotin peroxidase complex. Color Development by DAB. Hematoxylin counterstained.

Requested From: United States
Date Requested: 12/8/2016

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