Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MUC5AC antibody was raised against mucin isolated from an ovarian cyst fluid (pure endocervical type according to the Fenoglios classification). Splenocytes were fused with mouse myeloma SP2/0 cells.
Reacts with peptide core of gastric mucin (MUC5AC).
On formalin postfixed tissues, a protease pretreatment is recommended. Strongly reacts in IHC with ethanol fixed tissues. Reacts strongly in Western blot without beta-mercaptoethanol pretreatment of mucin solution.
MUC5AC Antibody, Gastric mucin Antibody, Major airway glycoprotein Antibody, Muc5/5ac Antibody, Mucin-5AC Antibody, LeB Antibody, Lewis B blood group antigen Antibody, Tracheobronchial mucin Antibody, TBM Antibody, MUC-5AC Antibody, MUC5 Antibody
MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is involved in epithelial cell proliferation and differentiation in adult airway mucosa and can be used as a marker for hypersecretory disorders. MUC5AC has also been observed in various tumors.