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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTM1 / Myotubularin Antibody (clone 1C10) LS‑C133331 Best Seller
Myotubularin antibody LS-C133331 is an unconjugated mouse monoclonal antibody to human Myotubularin (MTM1). Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C133331-100
100 µg
Unavailable

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Antibody
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

Myotubularin antibody LS-C133331 is an unconjugated mouse monoclonal antibody to human Myotubularin (MTM1). Validated for ELISA, IHC and WB.
About MTM1 / Myotubularin
Myotubularin (MTM1), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs in vitro and in vivo. MTM1 also has been shown to possess a SET-interacting domain (SID) which is unique to myotubularin-related proteins. Q13496 NM_000252 NP_000243.1

MTM1 Antibody, CNM Antibody, Mtmi Antibody, Myotubular myopathy 1 Antibody, Myotubularin Antibody, Myotubularin 1 Antibody, HMTM1 Antibody, MTMX Antibody, XLMTM Antibody, CG2 Antibody, RMTM Antibody


Specifications

Target
Human MTM1 / Myotubularin
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a,k Monoclonal [1C10]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (3 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MTM1 (AAH30779, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human MTM1
Usage
Immunohistochemistry: Formalin-fixed paraffin-embedded sections. RNAi Knockdown: Antibody validated. Sandwich ELISA: Recombinant protein. Western Blot: Transfected lysate, Recombinant protein.
Presentation
PBS, pH 7.4
Storage
Store at -20°C or lower. Aliquot to avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]

Western blot

Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.
Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.

RNA interference

Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.
Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]

Western blot

Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.
Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.

RNA interference

Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.
Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]

Western blot

Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.
Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.

RNA interference

Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.
Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.

Immunohistochemistry

Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]
Immunoperoxidase of monoclonal antibody to MTM1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 3 ug/ml]

Western blot

Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.
Western blot of MTM1 expression in transfected 293T cell line by MTM1 monoclonal antibody (M01), clone 1C10.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged MTM1 is approximately 1 ng/ml as a capture antibody.

RNA interference

Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.
Western blot of MTM1 over-expressed 293 cell line, cotransfected with MTM1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with MTM1 monoclonal antibody, clone 1C10. GAPDH ( 36.1 kD ) used as specificity a.


Requested From: 
Date Requested: 6/20/2018

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