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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTM1 / Myotubularin Antibody (aa566‑594) LS‑C98436
Myotubularin antibody LS-C98436 is an unconjugated rabbit polyclonal antibody to Myotubularin (MTM1) from human and mouse. Validated for WB.
Catalog
Size
Price
LS-C98436-400
400 µl
Unavailable

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Product Description

Myotubularin antibody LS-C98436 is an unconjugated rabbit polyclonal antibody to Myotubularin (MTM1) from human and mouse. Validated for WB.
About MTM1 / Myotubularin
Myotubularin (MTM1), a myotubularin-related phosphatase, has been shown to contain the consensus active site of dual specificity protein phosphatases (DSPs) and to share inhibition and inactivation characteristics with other DSPs in vitro and in vivo. MTM1 also has been shown to possess a SET-interacting domain (SID) which is unique to myotubularin-related proteins. Q13496 NM_000252 NP_000243.1

MTM1 Antibody, CNM Antibody, Mtmi Antibody, Myotubular myopathy 1 Antibody, Myotubularin Antibody, Myotubularin 1 Antibody, HMTM1 Antibody, MTMX Antibody, XLMTM Antibody, CG2 Antibody, RMTM Antibody


Specifications

Target
Human MTM1 / Myotubularin
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Ammonium sulfate precipitation
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E8478 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C98436. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa566-594
Specificity
This MTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 566-594 amino acids from the C-terminal region of human MTM1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.
Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.

Western blot

The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).
The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).

Western blot

Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.
Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.

Western blot

The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).
The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).

Western blot

Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.
Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.

Western blot

The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).
The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).

Western blot

Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.
Western blot showing knockdown of endogenous MTM1 expression by MTM1-targeting vectors pDM134 and pDM170. Embryonic stem (ES) cells were untreated (lane 1) or transfected with control plasmid pDCont (lane 2), MTM1-targeting plasmid pDM134 (lane 3), or pDM170 (lane 4). The blot was probed with anti-MTM1 rabbit polyclonal antibodies. -Actin was used as a loading control.

Western blot

The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).
The anti-MTM1 C-term antibody is used in Western blot to detect MTM1 in NCI-H460 cell lysate (lane 1) and in mouse heart tissue lysate (lane 2).


Requested From: 
Date Requested: 6/19/2018

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