MTBP / Mdm2-Binding Protein

Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, and MTBP, were recently discovered. The transcriptional activity of p53 is modulated by post translational regulations of the p53 protein including stabilization and acetylation. P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein. MDM2 inhibits both p53 mediated G1 arrest and apoptosis. A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.

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Products

Antibodies (17)

ELISA Kits (3)

Proteins (2)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (17)

Sandwich (1)

Target

MTBP / Mdm2-Binding Protein (22)

Reactivity

Human (19)

Mouse (8)

Rat (3)

Bat (3)

Bovine (3)

Chimpanzee (4)

Dog (3)

Gibbon (3)

Horse (3)

Monkey (3)

Pig (3)

Rabbit (3)

Xenopus (3)

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Application

IHC (5)

IHC-P (5)

WB (11)

Flo (1)

ELISA (4)

ICC (1)

IF (1)

Host

rabbit (16)

mouse (1)

Product Group

IHCPlus (2)

Isotype

IgG (11)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (16)

Clone

PHL-1 (1)

Format

96-Well Strip Plate (3)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

Unconjugated (11)

Epitope

aa139-188 (4)

aa122-139 (1)

aa667-812 (1)

aa853-881 (1)

Publications

No (22)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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IHC-plus™ MTBP / Mdm2-Binding Protein Antibody LS-B1378

(4.0) Rating

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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MTBP / Mdm2-Binding Protein Antibody (aa853-881) LS-C98397

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa853-881) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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IHC-plus™ MTBP / Mdm2-Binding Protein Antibody LS-B10863

(4.0) Rating

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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MTBP / Mdm2-Binding Protein Antibody LS-C672887

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MTBP / Mdm2-Binding Protein Antibody (HRP) LS-C672889

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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MTBP / Mdm2-Binding Protein Antibody (Biotin) LS-C672890

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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MTBP / Mdm2-Binding Protein Antibody (FITC) LS-C672892

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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MTBP / Mdm2-Binding Protein Antibody LS-C403343

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MTBP / Mdm2-Binding Protein Antibody (aa667-812, clone PHL-1) LS-C19034

Antibody:

MTBP / Mdm2-Binding Protein Mouse anti-Human Monoclonal (aa667-812) (PHL-1) Antibody

Reactivity:

Human, Chimpanzee

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$574

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MTBP / Mdm2-Binding Protein Antibody (aa122-139) LS-C83544

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa122-139) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$522

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MTBP / Mdm2-Binding Protein Antibody (aa139-188) LS-C201655

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa139-188) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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MTBP / Mdm2-Binding Protein Antibody (aa139-188, HRP) LS-C460069

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa139-188) (HRP) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MTBP / Mdm2-Binding Protein Antibody (aa139-188, Biotin) LS-C460067

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa139-188) (Biotin) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MTBP / Mdm2-Binding Protein Antibody (aa139-188, FITC) LS-C460068

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal (aa139-188) (FITC) Antibody

Reactivity:

Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Pig, Horse, Chimpanzee, Human, Monkey, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MTBP / Mdm2-Binding Protein Antibody LS-C832957

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

MTBP / Mdm2-Binding Protein Antibody LS-C747472

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

MTBP / Mdm2-Binding Protein Antibody LS-C816740

Antibody:

MTBP / Mdm2-Binding Protein Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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Human MTBP / Mdm2-Binding Protein (Sandwich ELISA) ELISA Kit - LS-F33889

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human MTBP / Mdm2-Binding Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86285

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

102 kDa

Price:

20 µg/$150

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MTBP / Mdm2-Binding Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110510

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

102 kDa

Price:

100 µg/$494

Select

Human MTBP / Mdm2-Binding Protein (Custom ELISA) ELISA Kit - LS-F16245

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse MTBP / Mdm2-Binding Protein (Custom ELISA) ELISA Kit - LS-F16246

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

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