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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MTBP / Mdm2‑Binding Protein Antibody (aa139‑188) LS‑C201655
Mdm2-Binding Protein antibody LS-C201655 is an unconjugated rabbit polyclonal antibody to Mdm2-Binding Protein (MTBP) from human, mouse, rat and other species. Validated for WB.
Catalog
Size
Price
LS-C201655-50
50 µg (1 mg/ml)
Unavailable

Popular MTBP / Mdm2-Binding Protein Products

Anti-MTBP antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1378 concentration 10 ug/ml.
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Applications: IHC, IHC - Paraffin, ICC, Western blot
Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with MTBP Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Anti-MTBP antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10863 concentration 7.5 ug/ml.
Species: Human
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Immunohistochemistry of Human brain using MTBP Polyclonal Antibody at dilution of 1:40.
Species: Human, Mouse
Applications: IHC, ELISA
Immunohistochemistry of Human thyroid cancer using MTBP Polyclonal Antibody at dilution of 1:20.
Species: Human, Mouse
Applications: IHC, ELISA

Product Description

Mdm2-Binding Protein antibody LS-C201655 is an unconjugated rabbit polyclonal antibody to Mdm2-Binding Protein (MTBP) from human, mouse, rat and other species. Validated for WB.
About MTBP / Mdm2-Binding Protein
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, and MTBP, were recently discovered. The transcriptional activity of p53 is modulated by post translational regulations of the p53 protein including stabilization and acetylation. Q96DY7 NM_022045 NP_071328.2

MTBP Antibody, Mdm2-binding protein Antibody, MDM2BP Antibody, HMTBP Antibody


Specifications

Target
Human MTBP / Mdm2-Binding Protein
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Pig, Rabbit, Xenopus (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
Synthetic peptide located between aa139-188 of human MTBP (B4DUR5). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Xenopus (100%); Panda, Zebra finch, Platypus (92%); Guinea pig, Turkey, Chicken (84%).
Epitope
aa139-188
Specificity
Human MTBP
Presentation
Lyophilized from PBS, 2% sucrose.
Reconstitution
50 µl Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of Human 293T. MTBP antibody dilution 1.0 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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