MTA2

metastasis associated 1 family, member 2

MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.

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Products

Antibodies (51)

Proteins (3)

ELISA Kits (2)

Type

Primary (51)

Recombinant (3)

Sandwich (2)

Target

MTA2 (56)

Reactivity

Human (44)

Mouse (24)

Rat (18)

Bat (15)

Bovine (16)

Chimpanzee (12)

Dog (13)

Gibbon (15)

Goat (9)

Guinea pig (6)

Horse (15)

Monkey (13)

Orangutan (9)

Pig (12)

Rabbit (15)

Xenopus (7)

Zebrafish (9)

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Application

IHC (13)

IHC-P (7)

WB (50)

Flo (2)

ELISA (4)

ICC (1)

IF (1)

IP (1)

Peptide-ELISA (1)

Host

rabbit (49)

mouse (2)

Product Group

IHCPlus (2)

Isotype

IgG (36)

IgG1 (1)

IgG2a (1)

Clonality

monoclonal mc (2)

polyclonal pc (49)

Format

96-Well Strip Plate (2)

APC (1)

APC Conjugated (1)

Biotin Conjugated (8)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (1)

Unconjugated (23)

Epitope

C-Terminus (12)

aa1-394 (8)

aa129-178 (4)

aa35-84 (4)

aa380-429 (4)

aa398-447 (4)

aa500-550 (1)

aa516-544 (1)

aa650-700 (1)

aa652-668 (1)

Publications

No (56)

Sample Type

Cell Lysates (2)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

GST, N-terminus (1)

His (1)

Species

Human (3)

Source

E. coli (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ MTA2 Antibody LS-B588

(4.0) Rating

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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IHC-plus™ MTA2 Antibody (aa650-700) LS-B1771

(4.0) Rating

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa650-700) Antibody

Reactivity:

Xenopus, Rat, Mouse, Dog, Bovine, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

MTA2 Antibody (C-Terminus) LS-C31938

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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MTA2 Antibody (C-Terminus, HRP) LS-C445379

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Goat, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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MTA2 Antibody (C-Terminus, Biotin) LS-C445376

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Goat, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

MTA2 Antibody (C-Terminus, FITC) LS-C445377

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Goat, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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MTA2 Antibody (aa516-544) LS-C98398

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa516-544) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MTA2 Antibody LS-C753554

Antibody:

MTA2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$371

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MTA2 Antibody LS-C332008

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Flo, IHC, WB

Format:

Unconjugated

Price:

20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539

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MTA2 Antibody LS-C753552

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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MTA2 Antibody LS-C831088

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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MTA2 Antibody LS-C746863

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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MTA2 Antibody LS-C832861

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

MTA2 Antibody (aa500-550) LS-C287286

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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MTA2 Antibody LS-C809062

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MTA2 Antibody (aa129-178) LS-C31880

Antibody:

MTA2 Rabbit anti-Mouse Polyclonal (aa129-178) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

MTA2 Antibody (aa380-429) LS-C31371

Antibody:

MTA2 Rabbit anti-Mouse Polyclonal (aa380-429) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

MTA2 Antibody LS-C125938

Antibody:

MTA2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

MTA2 Antibody LS-C783496

Antibody:

MTA2 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

25 µg/$281; 100 µg/$400

Select

MTA2 Antibody (aa652-668) LS-C83547

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa652-668) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$522

Select

MTA2 Antibody (C-Terminus) LS-C345818

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MTA2 Antibody (C-Terminus) LS-C31807

Antibody:

MTA2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

MTA2 Antibody (aa35-84) LS-C101566

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa35-84) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MTA2 Antibody (aa398-447) LS-C80127

Antibody:

MTA2 Rabbit anti-Human Polyclonal (aa398-447) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MTA2 Antibody LS-C834074

Antibody:

MTA2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$343; 120 µl/$427; 200 µl/$559

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