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Anti-MTA2 Antibody (aa652-668) LS-C83547

Note: This antibody replaces LS-C89525

Ordering

Wt. Vol. Conc. Price
100 µg - - $385
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular MTA2 Antibodies

Anti-MTA2 Antibody (C-Terminus) LS-C31938
Rabbit Polyclonal (IgG) to Human MTA2
Human, Monkey, Bat, Bovine, Goat, Horse, Rabbit
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MTA2 Antibody (aa52-8) IHC-plus™ LS-B588
Rabbit Polyclonal to Human MTA2
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MTA2 Antibody (aa650-700) IHC-plus™ LS-B1771
Rabbit Polyclonal (IgG) to Human MTA2
Human, Monkey, Mouse, Rat, Bovine, Dog, Xenopus
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MTA2
Human, Mouse, Rat
Western blot
Unconjugated

Details

Human MTA2
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

Western blot (0.5 - 1 µg/ml)

Specificity and Use

MTA2 antibody was raised against peptide corresponding to aa 652-668 of human PID/MTA2. This sequence differs from that of mouse by one amino acid.
aa652-668
Recognizes human, mouse, and rat PID/MTA2, a subunit of the nucleosome remodeling and deacetylating (NRD/NuRD) complex. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex, and its expression reduces the levels of acetylated p53. Deacetylation of p53 by PID/MTA2 represses p53- dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is expressed in a variety of tissues. Does not cross-react with MTA1.
Western Blot: A band of 75 kD is detected.

Packaging

PBS, pH 7.4, 0.02% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About MTA2

O94776 NM_004739 NP_004730.2

MTA2 Antibody, Metastasis-associated 1-like 1 Antibody, MTA1L1 Antibody, PID Antibody, MTA1-L1 Antibody, MTA1-L1 protein Antibody

MTA2 is a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling.

Requested From: United States
Date Requested: 12/4/2016

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