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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MSX2 / MSH Antibody (N‑Terminus) LS‑C109584
MSH antibody LS-C109584 is an unconjugated rabbit polyclonal antibody to MSH (MSX2) from human, bat, bovine and other species. Validated for WB.
Catalog
Size
Price
LS-C109584-50
50 µg
Unavailable

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Product Description

MSH antibody LS-C109584 is an unconjugated rabbit polyclonal antibody to MSH (MSX2) from human, bat, bovine and other species. Validated for WB.
About MSX2 / MSH
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter. P35548 NM_002449 NP_002440.2

MSX2 Antibody, CRS2 Antibody, HOX8 Antibody, Homeobox protein Hox-8 Antibody, Homeobox protein MSX-2 Antibody, Msh homeo box 2 Antibody, Parietal foramina 1 Antibody, PFM1 Antibody, MSH Antibody, Msh homeobox 2 Antibody, Msh homeobox homolog 2 Antibody, PFM Antibody, FPP Antibody


Specifications

Target
Human MSX2 / MSH
Host
Rabbit
Reactivity
Human, Monkey, Bat, Bovine, Dog, Horse (tested or 100% immunogen sequence identity)
Predicted
Mouse, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
MSX2 / MSH antibody was raised against synthetic peptide from N-Terminus of human MSX2 (P35548, NP_002440). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Tamarin, Panda, Dog, Bovine, Bat, Horse (100%); Mouse, Hamster (90%).
Blocking Peptide
LS-E10969 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C109584. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
N-Terminus
Specificity
Human MSX2
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
Distilled water
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MSX2 antibody LS-C109584 Western blot of Transfected 293T cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/20/2018

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