Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
IHC - Paraffin (4 µg/ml)
Specificity and Use
MST1R / RON antibody was raised against synthetic 18 amino acid peptide from C-terminus of human MST1R / RON. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Marmoset (94%); Mouse, Rat, Hamster, Elephant, Panda, Horse (89%); Dog, Bat (83%).
LS-E29237 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A7186. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human MST1R / RON. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
MST1R Antibody, C-met-related tyrosine kinase Antibody, CD136 Antibody, CDw136 Antibody, CD136 antigen Antibody, Friend virus susceptibility 2 Antibody, Fv2 Antibody, MSP receptor Antibody, p185-Ron Antibody, PTK8 protein tyrosine kinase 8 Antibody, RON Antibody, Soluble RON variant 3 Antibody, Soluble RON variant 1 Antibody, MST1R variant RON30 Antibody, Oncogene RON Antibody, PTK8 Antibody, MST1R variant RON62 Antibody, Protein-tyrosine kinase 8 Antibody, RON variant E2E3 Antibody, Soluble RON variant 2 Antibody, Soluble RON variant 4 Antibody
Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1.