Mouse MSR1 / CD204

Rat

Mouse (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

2F8

FITC. Also available Unconjugated or conjugated with RPE, Biotin.

Protein G purified

Unmodified

RAW264 cell line

Recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e. g. atherosclerotic lesions. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion. Recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.

• Flow Cytometry (1:10 - 1:50)
• Applications tested for the base form of this product only

PBS, 0.09% Sodium Azide, 1% BSA

Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light. Store undiluted.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P21757 NCBI: NM_002445 NP_002436.1