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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MSR1 / CD204 Antibody (clone 2F8, Biotin) LS‑C188109
CD204 antibody LS-C188109 is a biotin-conjugated rat monoclonal antibody to CD204 (MSR1) from mouse, channel catfish and pig. Validated for ELISA, Flow, IF, IHC, IP and WB.
Catalog
Size
Price
LS-C188109-100
100 µg (0.1 mg/ml)
Unavailable

Popular MSR1 / CD204 Products

Antibody
Species: Mouse
Applications: Flow Cytometry
Antibody
Species: Mouse, Pig, Channel catfish
Applications: Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Antibody
Species: Mouse
Applications: Flow Cytometry

Product Description

CD204 antibody LS-C188109 is a biotin-conjugated rat monoclonal antibody to CD204 (MSR1) from mouse, channel catfish and pig. Validated for ELISA, Flow, IF, IHC, IP and WB.
About MSR1 / CD204
MSR1 / CD204 is the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. P21757 NM_002445 NP_002436.1

MSR1 Antibody, CD204 antigen Antibody, SCARA1 Antibody, PhSR1 Antibody, SR-A Antibody, CD204 Antibody, PhSR2 Antibody, SRA Antibody, MSR2 Antibody


Specifications

Target
Mouse MSR1 / CD204
Host
Rat
Reactivity
Mouse, Pig, Channel catfish (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal [2F8]
Conjugations
Biotin. Also available Unconjugated or conjugated with FITC, RPE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunofluorescence
  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1)
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
  • IHC - Resin
Immunogen
MSR1 / CD204 antibody was raised against rAW264 cell line.
Specificity
Recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e. g. atherosclerotic lesions. Recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. Clone 2F8 is therefore unsuitable for use with the C57BL/6 mouse strain.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.09% sodium azide, 1% BSA
Storage
4°C or -20°C, Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.

Flow Cytometry

Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.
Flow cytometry of mouse peritoneal macrophages with Rat anti-Mouse CD204: Biotin This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/22/2018

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