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Anti-MSH6 Antibody (Internal, clone SPM525) LS-C210528


Wt. Vol. Conc. Price
- 500 µl - $360

LSBio (Direct) LSBio (Direct)

Other MSH6 Products

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Mouse Monoclonal [clone SPM525] (IgG1,k) to Human MSH6
IHC - Paraffin


Human MSH6
Human (tested or 100% immunogen sequence identity)
Human, Mouse, Bovine, Dog, Hamster, Rabbit (at least 90% immunogen sequence identity)
IgG1,k Monoclonal [SPM525]
Protein A/G purified


IHC - Paraffin (1:100)

Specificity and Use

MSH6 antibody was raised against synthetic peptide corresponding to internal region of human MSH6 protein.
Human MSH6
IMMUNOHISTOCHEMISTRY: Formalin-fixed, paraffin-embedded tissues are suitable for use with this primary antibody. Deparaffinization: Deparaffinize slides using xylene or xylene alternative and graded alcohols. Antibody Dilutions: If using the concentrate format of this product, dilute the antibody 1:100 prior to use. Antigen Retrieval: Boil tissue section in 10 mM Citrate buffer, pH 6.0 for 10-20 min followed by cooling at room temperature for 20 min. Primary Antibody: Incubate for 30 minutes at room temperature. Slide Washing: Slides must be washed in between steps. Rinse slides with PBS/0.05% Tween. Positive control: Colon carcinoma . Cellular localization: Nucleus.


PBS, pH 7.6, 1% BSA, 0.1% sodium azide
Store at 2-8°C. Do not freeze.
For research use only.

About MSH6

P52701 NM_000179 NP_000170.1

MSH6 Antibody, GTBP Antibody, HSAP Antibody, GTMBP Antibody, MutS (E. coli) homolog 6 Antibody, HMSH6 Antibody, Sperm-associated protein Antibody, p160 Antibody, G/T mismatch-binding protein Antibody, HNPCC5 Antibody, MutS homolog 6 (E. coli) Antibody, MutS-alpha 160 kDa subunit Antibody

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.


Immunohistochemistry of Human Colon Carcinoma stained with anti-MSH6 antibody

Requested From: United States
Date Requested: 11/28/2015

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