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Catalog Number	Size	Price
LS-C95606-0.1	0.1 ml	$283
LS-C95606-0.5	0.5 ml	$497
LS-C95606-1	1 ml	$729

Monoclonal Mouse anti‑Human MSH6 Antibody (clone 44, WB) LS‑C95606

Name: Anti-MSH6 Antibody | Mouse anti-Human Monoclonal IP,WB | LSBio
Brand: Lifespan BioSciences
SKU: LS-C95606-0.1
Price: 283.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Antibody:

MSH6 Mouse anti-Human Monoclonal (44) Antibody

Application:

WB, IP

Reactivity:

Human, Mouse, Rat, Dog

Format:

Unconjugated, Unmodified

$283

LS-C95606-0.1

$497

LS-C95606-0.5

$729

LS-C95606-1

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

MSH6 Mouse anti-Human Monoclonal (44) Antibody

Application:

WB, IP

Reactivity:

Human, Mouse, Rat, Dog

Format:

Unconjugated, Unmodified

Specifications

Description

MSH6 antibody LS-C95606 is an unconjugated mouse monoclonal antibody to MSH6 from human. It is reactive with human, mouse, rat and other species. Validated for IP and WB.

Target

Human MSH6

Synonyms

See All MSH6 Antibodies

Host

Mouse

Reactivity

Human, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)

Clonality

IgG1 Monoclonal

Clone

Conjugations

Unconjugated

Purification

Purified

Modifications

Unmodified

Immunogen

Synthetic human MSH6 peptide.

Specificity

MSH6 is a heterodimer of MSH2 and binds to DNA containing G/T mismatches. The MSH2-MSH6 complex recognizes a single-based mispair insertion/deletion loop. An alteration of microsatellite repeats is the result of slippage owing to strand misalignment during DNA replication and is referred to as microsatellite instability (MSI). These defects in DNA repair pathways have been related human carcinogenesis. Studies have shown the mutations of MLH-1, MSH2 and MSH6 genes contribute to the development of sporadic colorectal carcinoma. The repair of mismatch DNA is essential to maintaining the integrity of genetic information over time. cross reacts with mouse, rat and dog.

Applications