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Anti-MSH2 Antibody (aa637-665) LS-C164646

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

Most Popular MSH2 Antibodies

Anti-MSH2 Antibody (aa550-600) IHC-plus™ LS-B1973
Rabbit Polyclonal to Human MSH2
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-MSH2 Antibody (clone 3A2B8C) LS-C82158
Mouse Monoclonal [clone 3A2B8C] (IgG1) to Human MSH2
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-MSH2 Antibody (Internal, clone SP46) LS-C210308
Rabbit Monoclonal [clone SP46] (IgG) to Human MSH2
Human
IHC - Paraffin, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MSH2
Human
Immunofluorescence, Western blot, Flow Cytometry
Unconjugated

Details

Human MSH2
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • Immunofluorescence (1:10 - 1:50)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E1079 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C164646. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa637-665
This MSH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 637-665 amino acids from the Central region of human MSH2.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MSH2

P43246 NM_000251 NP_000242.1

MSH2 Antibody, COCA1 Antibody, FCC1 Antibody, HNPCC Antibody, HNPCC1 Antibody, MutS protein homolog 2 Antibody, HMSH2 Antibody, LCFS2 Antibody

Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA.

Western blot

Western blot
MSH2 Antibody western blot of SW480,U251 cell line lysates (35 ug/lane). The MSH2 antibody detected the MSH2 protein (arrow).

Flow Cytometry

Flow Cytometry
MSH2 Antibody flow cytometry of HeLa cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 3/26/2017

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