Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
MRVI1 antibody was raised against synthetic peptide located between aa51-100 of human MRVI1 (Q9Y6F6-3). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey, Mouse, Dog, Bovine, Bat, Rabbit, Horse, Pig, Guinea pig (100%).
MRVI1 Antibody, IRAG Antibody, JAW1-related protein MRVI1 Antibody, JAW1L Antibody, Protein MRVI1 Antibody
MRVI1 is similar to a putative mouse tumor suppressor gene (Mrvi1) that is frequently disrupted by mouse AIDS-related virus (MRV). The encoded protein, which is found in the membrane of the endoplasmic reticulum, is similar to Jaw1, a lymphoid-restricted protein whose expression is down-regulated during lymphoid differentiation. This protein is a substrate of cGMP-dependent kinase-1 (PKG1) that can function as a regulator of IP3-induced calcium release.