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Anti-MRPL46 Antibody (C-Terminus) LS-C145907

Catalog	Size	Price
LS-C145907-50	50 µg	Unavailable

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Anti-MRPL46 Antibody (aa80-160) LS-C384646

Antibody:	Rabbit Polyclonal (IgG) to Human MRPL46
Reactivity:	Human, Mouse, Rat
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Antibody:	Rabbit Polyclonal to Human MRPL46
Reactivity:	Human, Mouse, Rat, Guinea pig
Application:	Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human MRPL46
Host:	Rabbit
Reactivity:	Human, Mouse, Rat, Guinea pig (tested or 100% immunogen sequence identity)
Predicted:	Monkey, Bovine, Dog, Horse, Pig (at least 90% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Western blot
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

MRPL46 antibody was raised against synthetic peptide from C-Terminus of human MRPL46 (Q9H2W6, NP_071446). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Guinea pig (100%); Marmoset, Panda, Dog, Bovine, Horse, Pig (92%); Chicken (85%); Mouse, Rat, Elephant (84%).

Blocking Peptide:

LS-E22935 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C145907. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

C-Terminus

Specificity:

Human MRPL46

Packaging

Presentation:	Lyophilized from PBS with 2% sucrose
Reconstitution:	Distilled water
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About MRPL46

Uniprot: Q9H2W6 NCBI: NM_022163 NP_071446.2

Synonyms: MRPL46 Antibody, C15orf4 Antibody, L46mt Antibody, MRP-L46 Antibody, LIECG2 Antibody, p2ECSL Antibody

Description: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA.

(More About MRPL46)

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Western blot

MRPL46 antibody LS-C145907 Western blot of HeLa Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 8/22/2017

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