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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MRE11A / MRE11 Antibody LS‑C25661
Antibody
MRE11 antibody LS-C25661 is an unconjugated rabbit polyclonal antibody to MRE11 (MRE11A) from human and mouse. Validated for WB.
Catalog
Size
Price
LS-C25661-50
50 µl
Unavailable

Popular MRE11A / MRE11 Products

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Antibody
Species: Human
Applications: IHC, Western blot
Sample (10 ug of whole cell lysate) A: Yeast lysate 7.5% SDS PAGE MRE11A / MRE11 antibody diluted at 1:1000
Species: Yeast
Applications: Western blot

Product Description

MRE11 antibody LS-C25661 is an unconjugated rabbit polyclonal antibody to MRE11 (MRE11A) from human and mouse. Validated for WB.
About MRE11A / MRE11
Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. P49959 NM_005591 NP_005582.1

MRE11A Antibody, AT-like disease Antibody, Endo/exonuclease Mre11 Antibody, HNGS1 Antibody, MRE11 Antibody, MRE11 homolog 1 Antibody, MRE11 homolog A Antibody, MRE11B Antibody, ATLD Antibody


Specifications

Target
Human MRE11A / MRE11
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • Western blot (1:10000)
Immunogen
MRE11A / MRE11 antibody was raised against human Mre11 (full length) fusion protein.
Specificity
Specific for human Mre11 (full length). Species cross-reactivity: Human, mouse.
Usage
Western Blot: 1:10000 in human and mouse. Immunofluorescence: 1:200 in human (has not been tested in mouse) Immunoprecipitation: 3 ul for 3x1E6 cells (in human and mouse). Positive control: Hela whole cell lysate.
Presentation
PBS, pH 7.2, 0.02% sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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