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Anti-MRE11A / MRE11 Antibody (aa182-582) LS-C83535

Catalog Size Price
LS-C83535-100 100 µg Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG1) to Human MRE11A / MRE11
Western blot, Immunoprecipitation


Human MRE11A / MRE11
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


  • Western blot
  • Immunoprecipitation (1 - 5 µg/ml)

Specificity and Use

MRE11A / MRE11 antibody was raised against gST fusion protein corresponding to aa 182-582 of Mre11 expressed in E. coli.
Recognizes human Mre11, an 80 kD protein that acts as a Mn+2- dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin), and possibly other proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance.


PBS, pH 7.4
Store at -70°C, avoid freeze/thaw cycles.
For research use only.

About MRE11A / MRE11

P49959 NM_005591 NP_005582.1

MRE11A Antibody, AT-like disease Antibody, Endo/exonuclease Mre11 Antibody, HNGS1 Antibody, MRE11 Antibody, MRE11 homolog 1 Antibody, MRE11 homolog A Antibody, MRE11B Antibody, ATLD Antibody

Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity.

Requested From: 
Date Requested: 4/23/2018

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