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| Catalog Number | Size | Price |
|---|---|---|
| LS-B3899-50 | 50 µl (1 mg/ml) | $460 |
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PathPlus™ Monoclonal Mouse anti‑Human MPO / Myeloperoxidase Antibody (clone 9B12G7, IHC, WB) LS‑B3899
PathPlus™ Monoclonal Mouse anti‑Human MPO / Myeloperoxidase Antibody (clone 9B12G7, IHC, WB) LS‑B3899
Note: This antibody replaces LS-C108841, LS-C171445
Antibody:
MPO / Myeloperoxidase Mouse anti-Human Monoclonal (9B12G7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
MPO / Myeloperoxidase Mouse anti-Human Monoclonal (9B12G7) Antibody
Application:
IHC, IHC-P, WB, ELISA
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Myeloperoxidase (MPO) is a peroxidase enzyme that is highly expressed in neutrophil granulocytes. MPO produces hypohalous acids for antimicrobial processes and is the source of green coloration in pus and mucus. MPO may be a useful marker for cardiovascular diseases such as atherosclerosis, where increased concentrations of the protein have been linked to progression. In immunohistochemistry of normal tissue, it has positive cytoplasmic staining in neutrophils, Kupffer cells of the liver, and granulocytes such as eosinophils. In cancer, it is positive in myeloid leukemias and granulocytic sarcomas.
References: Journal of Leukocyte Biology. 2005 May. 77 (5): 598–625, PMID 15689384; Clin Chem. 2009 Aug;55(8):1462-70, PMID: 19556446
Target
Human MPO / Myeloperoxidase
Synonyms
MPO | Myeloperoxidase precursor | Myeloperoxidase
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
9B12G7
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Immunogen
Purified recombinant fragment of MPO (aa1-193) expressed in E. coli.
Specificity
Human
Applications
- IHC
- IHC - Paraffin (1:200 - 1:400)
- Western blot (1:100 - 1:500)
- ELISA (1:10000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B3899 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working dilution for LS-B3899 was determined to be 1:200.
Presentation
Ascitic fluid, 0.03% sodium azide
Storage
Short term: store at 4°C. Long term: store at -20°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About MPO / Myeloperoxidase
Validation
Anti-MPO / Myeloperoxidase antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-MPO / Myeloperoxidase antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Anti-MPO / Myeloperoxidase antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
See More About...
LSBio Ratings
PathPlus™ MPO / Myeloperoxidase Antibody (clone 9B12G7) for IHC, WB/Western, ELISA LS-B3899 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Mouse, Rat
Applications:
IHC, IHC - Frozen, Flow Cytometry
Species:
Mouse
Applications:
IHC, IHC - Frozen, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/19/2024
Date Requested: 4/19/2024
