MOB1A

MOB kinase activator 1A

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.

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Products

Antibodies (26)

Proteins (8)

ELISA Kits (3)

Type

Custom (3)

Over-Expression Lysate (2)

Primary (26)

Recombinant (6)

Target

MOB1A (37)

Reactivity

Human (27)

Mouse (16)

Rat (15)

Bat (3)

Bovine (6)

Chimpanzee (6)

Gibbon (6)

Guinea pig (6)

Horse (6)

Monkey (7)

Pig (6)

Rabbit (6)

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Application

IHC (14)

IHC-P (9)

WB (22)

Flo (4)

ELISA (13)

Peptide-ELISA (1)

Host

rabbit (24)

mouse (2)

Product Group

IHCPlus (1)

Isotype

IgG (13)

IgG1 (1)

IgG2b (1)

Clonality

monoclonal mc (2)

polyclonal pc (24)

Clone

2D3D11 (1)

3E7B2 (1)

Format

96-Well Strip Plate (3)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (17)

Epitope

aa2-216 (4)

aa81-130 (4)

C-Terminus (3)

70-150 aa, Internal (1)

aa167-216 (1)

aa188-216 (1)

aa5-33 (1)

Publications

No (37)

Tag

6His, C-terminus (2)

GST (1)

His (1)

His-SUMO (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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MOB1A Antibody (aa2-216) LS-C372130

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa2-216) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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MOB1A Antibody (aa2-216, HRP) LS-C372121

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa2-216) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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MOB1A Antibody (aa2-216, Biotin) LS-C372119

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa2-216) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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MOB1A Antibody (aa2-216, FITC) LS-C372117

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa2-216) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MOB1A Antibody (aa188-216) LS-C100567

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa188-216) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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MOB1A Antibody (aa167-216) LS-B11559

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa167-216) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

MOB1A Antibody (C-Terminus, HRP) LS-C473357

Antibody:

MOB1A Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MOB1A Antibody (C-Terminus, Biotin) LS-C473354

Antibody:

MOB1A Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MOB1A Antibody (C-Terminus, FITC) LS-C473355

Antibody:

MOB1A Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human MOB1A Protein (Recombinant 6His, C-terminus) (Ser2-Arg216) - LS-G38829

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

26kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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MOB1A Antibody LS-C406581

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

MOB1A Antibody (70-150 aa, Internal) LS-C384586

Antibody:

MOB1A Rabbit anti-Human Polyclonal (70-150 aa, Internal) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MOB1A Antibody LS-C826648

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MOB1A Antibody (clone 2D3D11) LS-C669457

Antibody:

MOB1A Mouse anti-Human Monoclonal (2D3D11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µl/$459

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MOB1A Antibody (clone 3E7B2) LS-C669459

Antibody:

MOB1A Mouse anti-Human Monoclonal (3E7B2) Antibody

Reactivity:

Human

Applications:

ELISA, Flo

Format:

Unconjugated

Price:

100 µl/$459

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MOB1A Antibody LS-C832214

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

MOB1A Antibody LS-C830707

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

Select

MOB1A Antibody (aa5-33) LS-C164259

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa5-33) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MOB1A Antibody LS-C666825

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$351

Select

MOB1A Antibody LS-C781231

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MOB1A Antibody LS-C804094

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MOB1A Antibody LS-C777997

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MOB1A Antibody LS-C778153

Antibody:

MOB1A Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MOB1A Antibody (aa81-130) LS-C205432

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa81-130) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MOB1A Antibody (aa81-130, FITC) LS-C472815

Antibody:

MOB1A Rabbit anti-Human Polyclonal (aa81-130) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• FITC

• Unconjugated
• FITC

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