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MNK / ATP7A
ATPase, Cu++ transporting, alpha polypeptide
MNK / ATP7A is a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed.
| Gene Name: | ATPase, Cu++ transporting, alpha polypeptide |
| Family/Subfamily: | Transporter , ATPase - P type, type IB |
| Synonyms: | ATP7A, Copper pump 1, Menkes disease ATPase, MNK, MK, SMAX3, Menkes syndrome, OHS, Copper-transporting ATPase 1, DSMAX, MC1 |
| Target Sequences: | NM_000052 NP_000043.4 Q04656 |
Publications (1)
1
Insulin promoted mobilization of GLUT4 from a perinuclear storage site requires RAB10. Alexandria Brumfield, Natasha Chaudhary, Dorothee Molle, Jennifer Wen, Johannes Graumann, Timothy E McGraw. Molecular biology of the cell. 2020 November;mbcE20060356. [Full Text Article]
[PubMed:33175605]
[PMC:PMC8098823]
Related Antibodies: LS-C209614.
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MNK / ATP7A Mouse anti-Human Monoclonal (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (Biotin) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Biotin Conjugated
100 µg/$475
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (FITC) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
FITC Conjugated
100 µg/$472
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (PerCP) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
PerCP Conjugated
100 µg/$478
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (Atto 488) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Atto 488 Conjugated
100 µg/$479
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (Atto 390) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Atto 390 Conjugated
100 µg/$479
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (Atto 594) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Atto 594 Conjugated
100 µg/$479
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (RPE) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
RPE Conjugated
100 µg/$477
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (APC) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
APC Conjugated
100 µg/$478
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (AP) (S60-4) Antibody
Mouse, Rat, Human
IHC, IHC-P, IP, WB
AP Conjugated
100 µg/$474
MNK / ATP7A Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$321
MNK / ATP7A Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$652
MNK / ATP7A Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
MNK / ATP7A Rabbit anti-Human Polyclonal (aa591-640) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
100 µl/$515
MNK / ATP7A Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ICC, IHC, WB
Unconjugated
100 µg/$919
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MNK / ATP7A Mouse anti-Human Monoclonal (aa42-61) (S60-4) Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
100 µg/$665
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MNK / ATP7A Mouse anti-Human Monoclonal (S60-4) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$537
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MNK / ATP7A Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MNK / ATP7A Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MNK / ATP7A Rabbit anti-Human Polyclonal (His640) Antibody
Mouse, Rat, Human
IHC
Unconjugated
50 µl/$321; 100 µl/$403
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