Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
A synthetic peptide from the middle region of human MMP-9.
Recognizes Matrix Metalloproteinase 9 (MMP-9, Collagenase 4, Gelatinase B). Species cross-reactivity: human and guinea pig. Does not react with mouse, rat and bovine.
Suitable for use in Western Blot. Western Blot: 2-4 ug/ml for 2 hours at RT. Positive control: Conditioned, serum-free medium from (TPA-treated) human fibrosarcoma HT-1080. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
10 mM PBS, pH 7.4.
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
MMP9 Antibody, 92kd gelatinase Antibody, 92 kd type iv collagenase Antibody, 92 kDa gelatinase Antibody, 92 kDa type IV collagenase Antibody, Matrix metalloproteinase-9 Antibody, MMP-9 Antibody, Type V collagenase Antibody, CLG4B Antibody, Gelatinase B Antibody, GELB Antibody, Macrophage gelatinase Antibody, MANDP2 Antibody
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens.