Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
MMP8 antibody was raised against nS0-derived recombinant rat rrMMP-8.
Recognizes rat MMP-8. Species cross-reactivity: rmMMP-8:100% and rhMMP-8:50%. Species sequence homology: mouse: 91%, dog: 75%, and human/chimpanzee; 73%.
Suitable for use in Western blot and Direct ELISA. Western blot:1-2 ug/ml. The detection limit for is ~5 ng/lane under non-reducing and reducing conditions. Direct ELISA: 0.5-1.0 ug/ml The detection limit is ~3 ng/well.
Lyophilized from PBS, 5% trehalose. Reconstitute, sterile PBS to a concentration of 0.5 mg/ml.
MMP8 is a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens.