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MMP7 / Matrilysin

matrix metallopeptidase 7 (matrilysin, uterine)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: matrix metallopeptidase 7 (matrilysin, uterine)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP7, Matrilysin, Matrin, MMP-7, MPSL1, PUMP-1, Pump-1 protease, MPMM, Uterine matrilysin, Punctuated metalloproteinase 1, Matrix metalloproteinase-7, PUMP1, Uterine metalloproteinase
Target Sequences: NM_002423 NP_002414.1 P09237

Publications (1)

1
Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells. Yang Liu, Min Zhu, Ruowen Gong, Xin Wang, Lei Li, Gezhi Xu. Frontiers in cell and developmental biology. 2020 August;8:608. [Full Text Article] [PubMed:32733897] [PMC:PMC7363772]

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Antibodies (95)
ELISA Kits (39)
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MMP7 / Matrilysin (146)
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MMP7 / Matrilysin Antibody - Anti-MMP7 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml.
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MMP7 / Matrilysin Goat anti-Human Polyclonal (aa255-267) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
MMP7 / Matrilysin Antibody - Anti-MMP7 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal (aa218-267) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
MMP7 / Matrilysin Antibody - Immunohistochemistry of paraffin-embedded human colon carcinoma using MMP7 antibodyat dilution of 1:100 (40x lens).
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$685
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Microplate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
78.13 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
MMP7 / Matrilysin ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$745
MMP7 / Matrilysin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$887
MMP7 / Matrilysin ELISA Kit
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Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$618
MMP7 / Matrilysin Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
MMP7 / Matrilysin Antibody - Western blot of MMP-7 antibody
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal (190-270 aa, C-terminal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MMP7 / Matrilysin Antibody - Immunodetection Analysis: Representative blot from a previous lot. Lane 1.recombinant proteinMMP7. The membrane blot was probed with anti-MMP7 primary antibody(0.25?g/ml). Proteins werevisualized using a goat anti-rabbit secondary antibodyconjugated to HRP and chemiluminescence detectionsystem. Arrows indicate cellular MMP7 from humanand mouse cells (35 kDa).
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
MMP7 / Matrilysin Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MMP7 / Matrilysin Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal (aa198-247) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
100 µl/$515
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MMP7 / Matrilysin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$832
MMP7 / Matrilysin Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-MMP7 mouse monoclonal antibody.  heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.0, 120C for 3min)
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MMP7 / Matrilysin Mouse anti-Human Monoclonal (aa95-267) (Carrier-free) (UMAB168) Antibody
Human
IHC, PMA, WB
Unconjugated, Carrier-free
100 µg/$539
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MMP7 / Matrilysin Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P
Unconjugated
100 µg/$919
MMP7 / Matrilysin Antibody - IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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MMP7 / Matrilysin Mouse anti-Human Monoclonal (aa95-267) (OTI3G7) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
MMP7 / Matrilysin Antibody - IHC of paraffin-embedded Human liver tissue using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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MMP7 / Matrilysin Mouse anti-Human Monoclonal (aa95-267) (OTI3E9) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
MMP7 / Matrilysin Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-MMP7 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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MMP7 / Matrilysin Mouse anti-Human Monoclonal (aa95-267) (OTI4H8) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
MMP7 / Matrilysin Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MMP7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-MMP7.
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MMP7 / Matrilysin Mouse anti-Human Monoclonal (aa95-267) (OTI2E1) Antibody
Human
WB
Unconjugated
100 µl/$434
MMP7 / Matrilysin Antibody - Western blot of recombinant MMP7 / MMP-7.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MMP7 / Matrilysin Rabbit anti-Human Polyclonal (aa1-267) Antibody
Mouse, Pig, Human
WB
Unconjugated
100 µl/$274; 200 µl/$301; 500 µl/$391; 1 ml/$437; 2 ml/$527; 5 ml/$889
MMP7 / Matrilysin Antibody - Immunohistochemistry - Anti-MMP-7 Antibody
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MMP7 / Matrilysin Rabbit anti-Mouse Polyclonal (aa95-264) Antibody
Mouse, Rat
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Viewing 1-25 of 146 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).