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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MMP16 Antibody LS‑C9085
MMP16 antibody LS-C9085 is an unconjugated rabbit polyclonal antibody to MMP16 from human and mouse. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C9085-100
100 µg
$725

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Product Description

MMP16 antibody LS-C9085 is an unconjugated rabbit polyclonal antibody to MMP16 from human and mouse. Validated for IHC and WB.
About MMP16
MMP16 is an endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells. P51512 NM_005941 NP_005932.2

MMP16 Antibody, C8orf57 Antibody, MMP-X2 Antibody, MT-MMP3 Antibody, MT3MMP Antibody, MT-MMP 3 Antibody, MT-MMP2 Antibody, MT2-MMP Antibody, Matrix metalloproteinase-16 Antibody, Membrane type 3-MMP Antibody, MMP-16 Antibody, MMPX2 Antibody, MT3-MMP Antibody, MTMMP3 Antibody


Specifications

Target
Human MMP16
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:20 - 1:50)
  • Western blot (1:250 - 1:500)
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MMP16 antibody was raised against synthetic peptide derived from hinge region of human MMP16.
Specificity
Recognizes the human membrane bound matrix metalloproteinase designated MMP16 (MT3-MMP). The antibody binds to an epitope in the hinge region of the protein and shows no cross-reactivity with other members of the MMP family. Species cross-reactivity: Human, mouse.
Usage
Immunohistochemistry: (frozen)- 1:20-1:50. Western Blot: 1:250-1:500.
Presentation
PBS, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/17/2018

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