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Anti-MMP16 Antibody (aa582-598) LS-C124070
Most Popular MMP16 Antibodies
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Details
| Human MMP16 | |
| Rabbit | |
| Human, Monkey, Mouse, Rat, Bovine, Dog, Horse, Pig, Chicken, Xenopus, Zebrafish (tested or 100% immunogen sequence identity) | |
| Bat, Hamster (at least 90% immunogen sequence identity) | |
| IgG Polyclonal | |
| Unconjugated | |
| Immunoaffinity purified | |
| Unmodified |
Applications
- IHC (0.5 - 1 µg/ml)
- Western blot (1 - 2 µg/ml)
Specificity and Use
| MMP16 antibody was raised against synthetic peptide corresponding to aa582-598, YTVFQFKRKGTPRHILY to human Matrix metalloproteinase-16. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Panda, Bovine, Dog, Horse, Pig, Opossum, Turkey, Chicken, Platypus, Lizard, Xenopus, Zebrafish (100%); Hamster, Bat, Seabass, Stickleback, Pufferfish (94%); Medaka (88%). | |
| aa582-598 | |
| Recognizes human Matrix metalloproteinase-16 at 70kD. Species cross-reactivity: rat. | |
| Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1-2 ug/ml. Immunohistochemistry: 0.5-1 ug/ml. |
Packaging
| Lyophilized from 5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg soidum azide | |
| Sterile distilled water | |
| Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. | |
| For research use only. |
About MMP16
P51512
NM_005941
NP_005932.2
MMP16 Antibody, C8orf57 Antibody, MMP-X2 Antibody, MT-MMP3 Antibody, MT3MMP Antibody, MT-MMP 3 Antibody, MT-MMP2 Antibody, MT2-MMP Antibody, Matrix metalloproteinase-16 Antibody, Membrane type 3-MMP Antibody, MMP-16 Antibody, MMPX2 Antibody, MT3-MMP Antibody, MTMMP3 Antibody
MMP16 is an endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
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Requested From:
Date Requested: 4/19/2018
Date Requested: 4/19/2018
