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Anti-MMP14 Antibody (aa319-333) LS-C8914

Catalog Size Price
LS-C8914-100 100 µg (2 mg/ml) Unavailable

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135 MMP14 Antibodies

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Anti-MMP14 Antibody (aa160-173) LS-C8915
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Anti-MMP14 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3338 concentration 10 ug/ml.
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Western blot of extracts from NIH-3T3 cells, using MMP-14 Antibody. The lane on the right is treated with the synthesized peptide.
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Anti-MMP14 Antibody (aa470-499) LS-C164235
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Confocal immunofluorescence of MMP14 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-mouse lgG (green). DAPI was used to stain the cell nuclear (blue).

100% Guaranteed
Mouse Monoclonal (IgG3,k) to Human MMP14
Human, Monkey, Mouse, Rat, Bovine, Goat, Hamster, Sheep
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)


Human MMP14
Human, Monkey, Mouse, Rat, Bovine, Goat, Hamster, Sheep (tested or 100% immunogen sequence identity)
Bat, Dog, Horse, Rabbit, Chicken (at least 90% immunogen sequence identity)
IgG3,k Monoclonal
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Immunoaffinity purified


  • IHC
  • IHC - Paraffin
  • IHC - Frozen
  • Western blot (10 µg/ml)
  • Immunoprecipitation
  • (applications tested for the base form of this product only)

Specificity and Use

MMP14 antibody was raised against peptide (aa 319-333, CDGNFDTVAMLRGEM) in the hemopexin-like domain of human membrane Type1 matrix metalloproteinase human MT1-MMP also referred to as MMP-14. Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Goat, Hamster, Porcine, Bovine, Opossum, Platypus (100%); Elephant, Panda, Stickleback, Turkey, Bat, Dog, Horse, Rabbit, Chicken, Pufferfish (93%); Zebrafish, Xenopus, Medaka (87%); Lizard (80%).
Recognizes human MT1-MMP. Very slight cross-reactivity to hMMP-3. Species cross-reactivity: Mouse, rat, rabbit porcine and equine. For unknown reasons this antibody does not react on westerns to MMP-14 [MT1-MMP], Human, Prodomain, Catalytic Domain.
Suitable for use in ELISA, Western Blot and Immunohistochemistry, and Immunoprecipitation. Western Blot: 10 ug/ml, membrane preparations; MD-MB-231 cells pretreated with 1-5 ug/ml ConA for 24-48 hours for positive control. 60-65kD proteins are identified. When tested against recombinant MT1-MMP (lacking the TM domain) expressed in CHO cells the antibody reacts with a band of ~59kD. Immunohistochemistry: Frozen sections; traditional formalin fixation problematic. Paraffin-embedded tissue sections with PLP fixation required.


PBS, pH 7.0, 2% BSA (protease free).
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About MMP14

P50281 NM_004995 NP_004986.1

MMP14 Antibody, Membrane type-1 MMP Antibody, MT1-MMP Antibody, MT1MMP Antibody, MT-MMP Antibody, MT-MMP 1 Antibody, Matrix metalloproteinase-14 Antibody, MMP-14 Antibody, MMP-X1 Antibody, MTMMP1 Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.

Requested From: 
Date Requested: 5/22/2018

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