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Anti-MMP14 Antibody (aa145-174) LS-C100444

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

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182 MMP14 Antibodies

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Anti-MMP14 Antibody (aa160-173) IHC-plus™ LS-B3338
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Anti-MMP14 Antibody (aa470-499) LS-C164235
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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MMP14
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human MMP14
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Pig, Cow (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E8125 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C100444. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa145-174
This MMP14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-174 amino acids from the N-terminal region of human MMP14.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MMP14

P50281 NM_004995 NP_004986.1

MMP14 Antibody, Membrane type-1 MMP Antibody, MT1-MMP Antibody, MT1MMP Antibody, MT-MMP Antibody, MT-MMP 1 Antibody, Matrix metalloproteinase-14 Antibody, MMP-14 Antibody, MMP-X1 Antibody, MTMMP1 Antibody

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
MMP14 Antibody (R160) western blot of NCI-H292 cell line lysates (35 ug/lane). The MMP14 antibody detected the MMP14 protein (arrow).

Flow Cytometry

Flow Cytometry
Flow cytometric of MCF-7 cells using MMP14 Antibody (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 4/25/2017

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