Target
Human MMP10
Synonyms
MMP10 | Matrix metalloproteinase-10 | SL-2 | STMY2 | Stromelysin 2 | Stromelysin-2 | MMP-10 | Transin 2 | Transin-2 | Stromelysin2 | Matrix metalloprotease 10
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Immunogen
Synthetic peptide from the C-Terminus of human MMP10 (FDENSQSMEQGFP, aa410-422 of UniProt P09238). Percent identity by BLAST analysis: Human, Cat, Elephant (100%); Rabbit (85%); Mouse (77%).
Applications
- Western blot (0.5 - 1 µg/ml)
Usage
Stromelysin-2 also known as matrix metalloproteinase-10 or transin-2 is an enzyme that in humans is encoded by the MMP10 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee