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MMP1

matrix metallopeptidase 1 (interstitial collagenase)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Gene Name: matrix metallopeptidase 1 (interstitial collagenase)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP1, CLG, Matrix metalloprotease 1, MMP-1, Interstitial collagenase, Matrix metalloproteinase 1, Matrix metalloproteinase-1
Target Sequences: NM_002421 NP_002412.1 P03956

Publications (3)

1
Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10<sub>) on Human Dermal Fibroblasts. Park SY, Byun EJ, Lee JD, Kim S, Kim HS. International journal of molecular sciences. 2018 September;19:pii E2727. [Full Text Article] [PubMed:30213068] [PMC:PMC6163910]
2
BRCA1 mutation influences progesterone response in human benign mammary organoids. Batzaya Davaadelger, Mi-Ran Choi, Hari Singhal, Susan E Clare, Seema A Khan, J Julie Kim. Breast cancer research : BCR. 2019 Nov;21:124. [Full Text Article] [PubMed:31771627] [PMC:PMC6878650]
3
Vitamin D and circulating tumor cells in primary breast cancer. Michal Mego, Barbora Vlkova, Gabriel Minarik, Zuzana Cierna, Marian Karaba, Juraj Benca, Tatiana Sedlackova, Dana Cholujova, Paulina Gronesova, Katarina Kalavska, Daniel Pindak, Jozef Mardiak, Peter Celec. Frontiers in oncology. 2022 September;12:950451. [Full Text Article] [PubMed:36158648] [PMC:PMC9489852]

☰ Filters
Antibodies (113)
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MMP1 (172)
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MMP1 Antibody - Anti-MMP1 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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MMP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
250 µl/$485
MMP1 Antibody - Immunohistochemical analysis of MMP1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MMP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
MMP1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$626
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MMP1 Protein - Recombinant Matrix Metalloproteinase 1 (MMP1) by SDS-PAGE
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E. coli
His, N-Terminal
23.8kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$818
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
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E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
42.7 kDa
2 µg/$268; 10 µg/$349
MMP1 Antibody - HT1080 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MMP1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
MMP1 Antibody - Immunofluorescence of HeLa cells using MMP1 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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MMP1 Mouse anti-Human Monoclonal (6A5) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µl/$459
MMP1 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MMP1 Guinea pig anti-Rabbit Polyclonal Antibody
Rabbit, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$485
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$834
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MMP1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$538
MMP1 Antibody - MMP1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human esophageal carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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MMP1 Rabbit anti-Human Polyclonal (aa317-347) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
MMP1 Antibody - Immunohistochemistry of paraffin-embedded human spleen using MMP1 antibody at dilution of 1:100.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MMP1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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MMP1 Mouse anti-Human Monoclonal (SB12e) Antibody
Human
ELISA, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$383
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
MMP1 Protein - Recombinant Matrix Metalloproteinase 1 By SDS-PAGE
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E. coli
His
21.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
MMP1 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
27.43 - 20000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$990
MMP1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
MMP1 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
24.69 - 18000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$588
MMP1 Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using MMP1 Polyclonal Antibody at dilution of 1:60.
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MMP1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MMP1 Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded human cervical cancer tissues (left) and Human Kidney cancer tissues (right) with DAB staining using MMP-1 Monoclonal Antibody.
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MMP1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
MMP1 Antibody - MMP1 Antibody in Immunohistochemistry (IHC)
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MMP1 Mouse anti-Human Monoclonal (6A5) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
Viewing 1-25 of 172 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).