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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MLH1 Antibody LS‑C9064
Antibody
MLH1 antibody LS-C9064 is an unconjugated rabbit polyclonal antibody to human MLH1. Validated for IHC, IP and WB.
Catalog
Size
Price
LS-C9064-50
50 µg
Unavailable

Popular MLH1 Products

Antibody
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Product Description

MLH1 antibody LS-C9064 is an unconjugated rabbit polyclonal antibody to human MLH1. Validated for IHC, IP and WB.
About MLH1
Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2. P40692 NM_000249 NP_000240.1

MLH1 Antibody, COCA2 Antibody, FCC2 Antibody, HMLH1 Antibody, HNPCC Antibody, HNPCC2 Antibody, MutL protein homolog 1 Antibody


Specifications

Target
Human MLH1
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot (1:500 - 1:5000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
MLH1 antibody was raised against synthetic peptide corresponding to a region of human MLH1 encoded within exon 20.
Specificity
Specific for human MLH1 (Homologue 1 of E. coli MutL Protein).
Usage
Suitable for use in Western Blot. Immunoprecipitation and Immunohistochemistry (Frozen). Western Blot: 1:500-1:5000. Immunoprecipitation:1-4 ug/mg protein.
Presentation
Tris-citrate/phosphate, 0.02% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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