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Anti-MLH1 Antibody (aa452-480) LS-C164215

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

Related Products

62 MLH1 Antibodies

Most Popular MLH1 Antibodies

Anti-MLH1 Antibody (clone G168-15) LS-C95607
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IHC - Paraffin
Unconjugated
Anti-MLH1 Antibody IHC-plus™ LS-B3475
Mouse Monoclonal (IgG1) to Human MLH1
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Immunohistochemistry Image
Anti-MLH1 Antibody LS-C109333
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Human
ICC, Immunofluorescence, Western blot
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Anti-MLH1 Antibody (clone M1) LS-C133324
Mouse Monoclonal [clone M1] (IgG) to Human MLH1
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Anti-MLH1 Antibody (Internal) LS-C210492
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100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human MLH1
Human
Western blot, Flow Cytometry
Unconjugated

Details

Human MLH1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E1153 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C164215. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa452-480
This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About MLH1

P40692 NM_000249 NP_000240.1

MLH1 Antibody, COCA2 Antibody, FCC2 Antibody, HMLH1 Antibody, HNPCC Antibody, HNPCC2 Antibody, MutL protein homolog 1 Antibody

Heterodimerizes with PMS2 to form MutL alpha, a component of the post-replicative DNA mismatch repair system (MMR). DNA repair is initiated by MutS alpha (MSH2-MSH6) or MutS beta (MSH2-MSH6) binding to a dsDNA mismatch, then MutL alpha is recruited to the heteroduplex. Assembly of the MutL-MutS-heteroduplex ternary complex in presence of RFC and PCNA is sufficient to activate endonuclease activity of PMS2.

Western blot

Western blot
MLH1 Antibody western blot of K562 cell line lysates (35 ug/lane). The MLH1 antibody detected the MLH1 protein (arrow).

Flow Cytometry

Flow Cytometry
MLH1 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 4/23/2017

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