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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MLC2 / MYL9 Antibody (phospho‑Ser19, clone 4i15) LS‑C16676
MYL9 antibody LS-C16676 is an unconjugated mouse monoclonal antibody to MYL9 (MLC2) from human, mouse, rat and other species. Validated for IF and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C16676-100
100 µl
$575

Popular MLC2 / MYL9 Products

Anti-MYL9 antibody IHC of human smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 2.5 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Immunohistochemistry of paraffin-embedded human liver cancer tissue using MYL9 antibody.
Species: Human, Mouse, Rat
Applications: IHC, Western blot
Anti-MYL9 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Species: Mouse, Human, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot
Anti-MYL9 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Applications: IHC, IHC - Paraffin, Western blot

Product Description

MYL9 antibody LS-C16676 is an unconjugated mouse monoclonal antibody to MYL9 (MLC2) from human, mouse, rat and other species. Validated for IF and WB. Cited in 1 publication.

Specifications

Target
Human MLC2 / MYL9
Synonyms
MYL9, 20 kDa myosin light chain, LC20, MLC-2C, MLC2, Myosin RLC, MRLC1, MYRL2
Host
Mouse
Reactivity
Human, Mouse, Rat, Bovine, Pig (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [4i15]
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Applications
  • Immunofluorescence (1:200)
  • Western blot (1:1000)
Immunogen
MLC2 / MYL9 antibody was raised against phospho-peptide corresponding to residues surroundingSer19 of human myosin light chain 2 (smooth muscle) (KLH coupled).
Epitope
pSer19
Specificity
Detects endogenous levels of human myosin light chain 2 (smooth muscle) only when phosphorylated at serine 19 at 18kD. Does not cross-react with the cardiac isoform of myosin light chain 2. Species cross-reactivity: mouse and rat.
Usage
Suitable for use in ELISA, Western Blot, Immunohistochemistry, and Immunocytochemistry. Western Blot: 1:1000. Immunohistochemistry: 1:100. Immunocytochemistry: (IF) 1:50.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About MLC2 / MYL9
Myosin, the major component of muscle filaments, is a long asymmetric molecule containing a globular head and a long tail. It is composed of two heavy chains and four light chains. Phosphorylation of myosin light chain in response to increased calcium levels leads to contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. P24844 NM_006097 NP_006088.2


Publications (1)

1
Morgana acts as an oncosuppressor in chronic myeloid leukemia. Panuzzo C, Rocca S, Familiari U, Piazza R, Crivellaro S, Carr[Character e0] G, Ferretti R, Fusella F, Giugliano E, Camporeale A, Franco I, Miniscalco B, Cutrin JC, Turco E, Silengo L, Hirsch E, Rege-Cambrin G, Gambacorti-Passerini C, Pandolfi PP, Papotti M, Saglio G, Tarone G, Morotti A, Brancaccio M. Blood. Feb; [Full Text Article] [PubMed:25678499]

Customer Reviews (0)


Requested From: United States
Date Requested: 11/13/2018

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