MKNK2 / MNK2

MAP kinase interacting serine/threonine kinase 2

MKNK2 / MNK2 is a member of the calcium/calmodulin-dependent protein kinases (CAMK) Ser/Thr protein kinase family, which belongs to the protein kinase superfamily. This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs, and an N-terminal polybasic region which binds importin A and the translation factor scaffold protein eukaryotic initiation factor 4G (eIF4G). This protein is one of the downstream kinases activated by mitogen-activated protein (MAP) kinases. It phosphorylates the eukaryotic initiation factor 4E (eIF4E), thus playing important roles in the initiation of mRNA translation, oncogenic transformation and malignant cell proliferation. In addition to eIF4E, this protein also interacts with von Hippel-Lindau tumor suppressor (VHL), ring-box 1 (Rbx1) and Cullin2 (Cul2), which are all components of the CBC(VHL) ubiquitin ligase E3 complex. Multiple alternatively spliced transcript variants have been found, but the full-length nature and biological activity of only two variants are determined. These two variants encode distinct isoforms which differ in activity and regulation, and in subcellular localization.

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Products

Antibodies (41)

Proteins (8)

Type

Over-Expression Lysate (4)

Primary (41)

Recombinant (4)

Target

MKNK2 / MNK2 (49)

Reactivity

Human (35)

Mouse (17)

Rat (10)

Bat (3)

Bovine (1)

Chicken (1)

Chimpanzee (3)

Dog (3)

Guinea pig (4)

Horse (3)

Monkey (3)

Non-Human Primate (2)

Pig (3)

Sheep (1)

Zebrafish (3)

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Application

IHC (4)

IHC-P (4)

WB (41)

ELISA (22)

IF (1)

Peptide-ELISA (1)

Host

rabbit (40)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (32)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (40)

Clone

4F11 (1)

Format

APC Conjugated (4)

Azide-free (3)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (18)

Epitope

aa36-64 (7)

aa402-432 (7)

aa70-100 (7)

aa36-85 (4)

Internal (1)

Publications

No (49)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (1)

Select

MKNK2 / MNK2 Antibody (aa36-85) LS-B3999

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa36-85) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

MKNK2 / MNK2 Antibody (aa36-85, HRP) LS-C460027

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MKNK2 / MNK2 Antibody (aa36-85, Biotin) LS-C460025

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MKNK2 / MNK2 Antibody (aa36-85, FITC) LS-C460026

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Bat, Mouse, Dog, Guinea pig, Rat, Human, Monkey, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MKNK2 / MNK2 Antibody (clone 4F11) LS-C197340

Antibody:

MKNK2 / MNK2 Mouse anti-Human Monoclonal (4F11) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

MKNK2 / MNK2 Antibody (aa70-100) LS-C98993

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa70-100) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MKNK2 / MNK2 Antibody (aa36-64) LS-C164486

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa36-64) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

MKNK2 / MNK2 Antibody (aa36-64) LS-C329834

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MKNK2 / MNK2 Antibody (aa36-64, Biotin) LS-C223284

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa36-64, FITC) LS-C223285

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa36-64, APC) LS-C223283

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa36-64, PE) LS-C223288

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa36-64, Azide-free, HRP) LS-C223286

Antibody:

MKNK2 / MNK2 Rabbit anti-Mouse Polyclonal (aa36-64) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

MKNK2 / MNK2 Antibody LS-C666786

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

MKNK2 / MNK2 Antibody (aa402-432) LS-C327828

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa402-432) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MKNK2 / MNK2 Antibody (aa402-432, Biotin) LS-C225807

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa402-432) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa402-432, FITC) LS-C225806

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa402-432) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa402-432, APC) LS-C225804

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa402-432) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa402-432, Azide-free, HRP) LS-C225808

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa402-432) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free

Select

MKNK2 / MNK2 Antibody (aa70-100) LS-C327827

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa70-100) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MKNK2 / MNK2 Antibody (aa70-100, APC) LS-C225811

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa70-100) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MKNK2 / MNK2 Antibody (aa70-100, Azide-free, HRP) LS-C225813

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (aa70-100) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• APC
• HRP, Azide-free

• Unconjugated
• APC
• HRP, Azide-free

Select

MKNK2 / MNK2 Antibody (Internal) LS-C384592

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

MKNK2 / MNK2 Antibody LS-C824927

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MKNK2 / MNK2 Antibody LS-C804035

Antibody:

MKNK2 / MNK2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Viewing 1-25 of 49 product results

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