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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MKNK1 / MNK1 Antibody (phospho‑Thr197/Thr202) LS‑C16582
MNK1 antibody LS-C16582 is an unconjugated rabbit polyclonal antibody to MNK1 (MKNK1) from human, mouse and rat. Validated for ELISA and WB.
Antibody
Catalog
Size
Price
LS-C16582-100
100 µl
$575

Popular MKNK1 / MNK1 Products

Anti-MKNK1 / MNK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Anti-MKNK1 / MNK1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Anti-MKNK1 / MNK1 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Peptide Enzyme-Linked Immunosorbent Assay
Western blot analysis of lysates from HUVEC cells, using MKNK1 Antibody. The lane on the right is blocked with the synthesized peptide.
Species: Human, Mouse
Applications: Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

MNK1 antibody LS-C16582 is an unconjugated rabbit polyclonal antibody to MNK1 (MKNK1) from human, mouse and rat. Validated for ELISA and WB.

Specifications

Target
Mouse MKNK1 / MNK1
Synonyms
MKNK1, MNK1, MAPK-Interacting Kinase 1
Host
Rabbit
Reactivity
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • ELISA
Failed Applications
  • IHC - Paraffin
Immunogen
MKNK1 / MNK1 antibody was raised against synthetic phosphopeptide corresponding to residues surrounding Thr197 and Thr202 of mouse Mnk1 (KLH).
Epitope
pThr197/Thr202
Specificity
Recognizes endogenous levels of mouse Mnk1 only when phosphorylated at Thr197/202. Cross-reacts with phosphorylated Mnk2a and Mnk2b. Species cross-reactivity: Human, monkey and rat.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1:1000.
Presentation
10 mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 50% Glycerol, No preservatives added
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
About MKNK1 / MNK1
May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap. Q9BUB5 NM_003684 NP_003675.2


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Requested From: United States
Date Requested: 11/15/2018

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